Questions tagged [genetics]

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"Just before he died, (Gregor) Mendel requested that an extensive autopsy be done." Why? Was he simply "very enthusiastic for all kinds of research"?

NPR's December 30, 2022 article Why scientists dug up the father of genetics, Gregor Mendel, and analyzed his DNA includes speculation by those involved about whether Mendel would want his body to be ...
uhoh's user avatar
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3 votes
1 answer
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What did Kaspar contribute to the gene therapy for spinal muscular atrophy?

I've read on KEI website that in the early 2000s Dr Martine Barkats, from France, successfuly treated mice with spinal muscular atrophy (SMA) with an AAV9 viral vector; and that Dr Brian Kaspar, an ...
Hinko Pih Pih's user avatar
3 votes
1 answer
371 views

When and why was the symbol $w$ introduced for biological fitness?

$w$ the visually similar $\omega$ are often used to represent biological fitness in population genetics models. (Sometimes $W$ is used for absolute fitness, and $w$ for relative fitness.) These ...
Mars's user avatar
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7 votes
3 answers
292 views

Why didn't Mendel's experiments draw attention until the 20th century?

In The Gene: An Intimate History, author concludes the Mendel's pea experiments publication by these words: Mendel himself requested forty reprints, which he mailed, heavily annotated, to many ...
Failed Scientist's user avatar
7 votes
1 answer
219 views

How was Mendel's work rediscovered after being forgotten for 45 years?

According to Melanie Mitchell's book, Complexity: A Guided Tour [PDF], Mendel's model [...] was published in a rather obscure journal and was not appreciated as being of great importance until 1900, ...
Ooker's user avatar
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7 votes
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451 views

Who first suggested, contra the central dogma, that "junk" DNA may perform epigenetic functions?

There were in last several years papers in Science regarding DNA that does not code for any protein ("junk" DNA) as having epigenetic aspects, namely, switching on and off other genes and thus ...
Gottfried William's user avatar
3 votes
1 answer
106 views

Francis Crick and the usefulness of "genes" as compared to molecular biochemistry

In lecture 12 of Professor John R. Searle's U.C. Berkeley class, "Philosophy of Mind", he remarks [18m22s]: We no longer talk mysteriously about how heredity works. We can actually identify ...
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2 votes
1 answer
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Who was the Northern California pioneer of genetics?

I was telling a friend about a pioneer researcher in genetics who did his work in Northern California around the late 1800s. I was thinking this was in Marin, Sonoma, or Napa County. When I tried to ...
Michael Geary's user avatar