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Questions tagged [genetics]

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3
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1answer
70 views

What did Kaspar contribute to the gene therapy for spinal muscular atrophy?

I've read on KEI website that in the early 2000s Dr Martine Barkats, from France, successfuly treated mice with spinal muscular atrophy (SMA) with an AAV9 viral vector; and that Dr Brian Kaspar, an ...
4
votes
2answers
146 views

Why Mendel's experiments didn't draw attention until 20th century?

In The Gene: An Intimate History, author concludes the Mendel's pea experiments publication by these words: Mendel himself requested forty reprints, which he mailed, heavily annotated, to many ...
5
votes
1answer
129 views

How was Mendel's work rediscovered after 45 years of forgotten?

According to the book Complexity: A Guided Tour, Mendel's model "was published in a rather obscure journal and was not appreciated as being of great importance until 1900, after which several ...
7
votes
1answer
384 views

Who first suggested, contra the central dogma, that “junk” DNA may perform epigenetic functions?

There were in last several years papers in Science regarding DNA that does not code for any protein ("junk" DNA) as having epigenetic aspects, namely, switching on and off other genes and thus ...