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Need quote from early 20th century about humanity probably never being able to control (manipulate, see?) a single quantum system

I remember having read a statement, I think by one of the founding fathers of quantum mechanics, that we will probably never be able to control (or manipulate or see or isolate...?) a single quantum system (or atom).

The quote was used to highlight the fast progress experimental quantum physics has made over the last few decades (seeing that single-particle control is routinely achieved in experiments).

Does anyone know the quote and its source?