I propose this as a companion wiki page to the one about PhD dissertations which contain a solution to an open problem in the style of big-list
questions, thinking in terms of the well-known paradigm that splits mathematical research into problem solving and theory building. Theories are at times developed to solve famous open problems, but sometimes the concrete problems they solve are quickly dwarfed by the possibilities that a new theory opens.
Can you name modern mathematicians who already in their PhD theses (or earlier in their career) developed a substantial new theory or laid the foundations of a new field of research?